Percentage of Recurring Anomalies

Option List:
A. 1 in 1
B. 1 in 2
C. 1 in 5
D. 1 in 10
E. 1 in 20
F. 1 in 25
G. 1 in 100
H. 1 in 150
I. 1 in 200
J. 1 in 500
K. 1 in 1000
Each of the following clinical scenarios below relate to women seeking pre-conception advice. For each patient select the SINGLE most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. Mr &Mrs, Adams are here for pre conceptional counselling as this couple have had three children, two of which have had congenital heart disease. They ask your advice about the chance of a further pregnancy being similarly affected by congenital heart disease.

2. Ms. Rachel , A 28 year old woman had an open spina bifida lesion closed in the early neonatal period and subsequently she relies on a wheelchair for mobility and intermittent self catheterisation. She is seeking your advice about the chance of her having a baby similarly affected by a neural tube defect.

3. Mrs. Ruby, A 40  year old woman has a long history of infertility and is contemplating assisted conception treatment. She asks you what is the risk of having a baby with trisomy 21 at her age?

4. Mrs. Gilchrist , 32 year old , A woman has HIV infection and wishes to become pregnant. She is taking highly active anti-retroviral treatment and has an undetectable viral load. She asks you what the chance is of her baby becoming infected with HIV.

5. Ms. Natash, 26 year old woman is in preconceptions clinic. She has two babies, both of them have an open spina bifida lesion closed in the early neonatal period She is seeking your advice about the chance of her having a baby similarly affected by a neural tube defect.