Recurrent Pregnancy Loses Recurrent Pregnancy Loses Option List:A. 2 or more pregnancy lossB. RPL without a previous ongoing pregnancy (viable pregnancy)C. Spontaneous demise of fetus before 20 weeksD. RPL after one or more previous pregnancies progressing beyond 24 weeks’ gestationE. Spontaneous demise of the fetus before 22 weeksF. Spontaneous demise of fetus before 24 weeksG. 3 or more pregnancy lossChoose the most appropriate answers from the box given above:1. Definition of pregnancy loss ? Please select your answer A. 2 or more pregnancy loss B. RPL without a previous ongoing pregnancy (viable pregnancy) C. Spontaneous demise of fetus before 20 weeks D. RPL after one or more previous pregnancies progressing beyond 24 weeks’ gestation E. Spontaneous demise of the fetus before 22 weeks F. Spontaneous demise of fetus before 24 weeks G. 3 or more pregnancy loss 2. Definition of recurrent pregnancy loss Please select your answer A. 2 or more pregnancy loss B. RPL without a previous ongoing pregnancy (viable pregnancy) C. Spontaneous demise of fetus before 20 weeks D. RPL after one or more previous pregnancies progressing beyond 24 weeks’ gestation E. Spontaneous demise of the fetus before 22 weeks F. Spontaneous demise of fetus before 24 weeks G. 3 or more pregnancy loss 3. Definition of Primary RPL Please select your answer A. 2 or more pregnancy loss B. RPL without a previous ongoing pregnancy (viable pregnancy) C. Spontaneous demise of fetus before 20 weeks D. RPL after one or more previous pregnancies progressing beyond 24 weeks’ gestation E. Spontaneous demise of the fetus before 22 weeks F. Spontaneous demise of fetus before 24 weeks G. 3 or more pregnancy loss 4. Definition of secondary RPL Please select your answer A. 2 or more pregnancy loss B. RPL without a previous ongoing pregnancy (viable pregnancy) C. Spontaneous demise of fetus before 20 weeks D. RPL after one or more previous pregnancies progressing beyond 24 weeks’ gestation E. Spontaneous demise of the fetus before 22 weeks F. Spontaneous demise of fetus before 24 weeks G. 3 or more pregnancy loss Choose the most appropriate answer for the statements given belowOption List A. Pelvic 3D ultrasoundB. Conventional KaryotypingC. HLA class II determination is recommendedD. MRI Pelvis to rule out anatomical factorsE. Screening for APA antibodiesF. Parental karyotyping for the coupleG. Hereditary thrombophilia screeningH. Screening for APA antibodies only if three or more pregnancy lossesI. TSH, Anti-TPO antibodies, Lupus Anticoagulant, ACA-IgG &IgMJ. CGH-array for the purpose of explanation of a causeK. HLA Class C determination is recommendedL. Screening for hereditary thrombophilias after 4 weeks M. Cytokine evaluation is recommended5. Ms. Sherley, 27 years old attended the RPL clinic with previous 2 pregnancy losses and now at 7 weeks of pregnancy found to have missed miscarriage.She has been counselled for termination of pregnancy. What karyotyping would be offered to her? Please select your answer A. Pelvic 3D ultrasound B. Conventional Karyotyping C. HLA class II determination is recommended D. MRI Pelvis to rule out anatomical factors E. Screening for APA antibodies F. Parental karyotyping for the couple G. Hereditary thrombophilia screening H. Screening for APA antibodies only if three or more pregnancy losses I. TSH, Anti-TPO antibodies, Lupus Anticoagulant, ACA-IgG &IgM J. CGH-array for the purpose of explanation of a cause K. HLA Class C determination is recommended L. Screening for hereditary thrombophilias after 4 weeks M. Cytokine evaluation is recommended 6. Ms. Linda, 24 years, with history of two previous pregnancy losses is attending the RPL clinic for investigations. The choice of investigation that would be offered is Please select your answer A. Pelvic 3D ultrasound B. Conventional Karyotyping C. HLA class II determination is recommended D. MRI Pelvis to rule out anatomical factors E. Screening for APA antibodies F. Parental karyotyping for the couple G. Hereditary thrombophilia screening H. Screening for APA antibodies only if three or more pregnancy losses I. TSH, Anti-TPO antibodies, Lupus Anticoagulant, ACA-IgG &IgM J. CGH-array for the purpose of explanation of a cause K. HLA Class C determination is recommended L. Screening for hereditary thrombophilias after 4 weeks M. Cytokine evaluation is recommended 7. Ms. Tina, 30years with history of two previous miscarriages at around 11 weeks, the miscarriage occurred 15 days back, has now come to RPL clinic.She gives a history of venous thromboembolism. The investigation of choice for her would be Please select your answer A. Pelvic 3D ultrasound B. Conventional Karyotyping C. HLA class II determination is recommended D. MRI Pelvis to rule out anatomical factors E. Screening for APA antibodies F. Parental karyotyping for the couple G. Hereditary thrombophilia screening H. Screening for APA antibodies only if three or more pregnancy losses I. TSH, Anti-TPO antibodies, Lupus Anticoagulant, ACA-IgG &IgM J. CGH-array for the purpose of explanation of a cause K. HLA Class C determination is recommended L. Screening for hereditary thrombophilias after 4 weeks M. Cytokine evaluation is recommended 8. Ms. Regan, 26 years, with previous 2 pregnancy losses (8 & 9 weeks respectively) has attended the RPL clinic, she should be advised to undergo Please select your answer A. Pelvic 3D ultrasound B. Conventional Karyotyping C. HLA class II determination is recommended D. MRI Pelvis to rule out anatomical factors E. Screening for APA antibodies F. Parental karyotyping for the couple G. Hereditary thrombophilia screening H. Screening for APA antibodies only if three or more pregnancy losses I. TSH, Anti-TPO antibodies, Lupus Anticoagulant, ACA-IgG &IgM J. CGH-array for the purpose of explanation of a cause K. HLA Class C determination is recommended L. Screening for hereditary thrombophilias after 4 weeks M. Cytokine evaluation is recommended 9. Ms. Retty Sampson, 25 years with three previous second trimester miscarriages at 14 weeks, 16 weeks and 16 weeks respectively has attended the RPL clinic. The best investigation of choice is Please select your answer A. Pelvic 3D ultrasound B. Conventional Karyotyping C. HLA class II determination is recommended D. MRI Pelvis to rule out anatomical factors E. Screening for APA antibodies F. Parental karyotyping for the couple G. Hereditary thrombophilia screening H. Screening for APA antibodies only if three or more pregnancy losses I. TSH, Anti-TPO antibodies, Lupus Anticoagulant, ACA-IgG &IgM J. CGH-array for the purpose of explanation of a cause K. HLA Class C determination is recommended L. Screening for hereditary thrombophilias after 4 weeks M. Cytokine evaluation is recommended 10. Ms. Lesslie, 29 years, has attended the RPL clinic with history of three pregnancy losses. She has delivered a boy before her consecutive pregnancy losses. She has been investigated for harmonal causes, acquired thrombophilias, and also for anatomical factors and were found to be normal. The investigation that should be offered to her is Please select your answer A. Pelvic 3D ultrasound B. Conventional Karyotyping C. HLA class II determination is recommended D. MRI Pelvis to rule out anatomical factors E. Screening for APA antibodies F. Parental karyotyping for the couple G. Hereditary thrombophilia screening H. Screening for APA antibodies only if three or more pregnancy losses I. TSH, Anti-TPO antibodies, Lupus Anticoagulant, ACA-IgG &IgM J. CGH-array for the purpose of explanation of a cause K. HLA Class C determination is recommended L. Screening for hereditary thrombophilias after 4 weeks M. Cytokine evaluation is recommended Option ListA. Low dose AspirinB.Serial Cervical length ultrasound scanC. PrednisoloneD. HCGE. Low molecular weight HeparinF. MetforminG. Hysteroscopic resection H. Intravenous immunoglobulin I. Cervical cerclageJ. ReassuranceK. Progesterone pessaryL. Low dose Aspirin & LMW HeparinM. Weight reductionChoose the single most appropriate management plan for the followingStatements:Each option may be used once, more than once, or not at all. 11. A 28 year old lady presents at 10 weeks gestation with vaginal spotting. She gives history of one first trimester pregnancy loss and one second trimester pregnancy loss at 18 weeks suspected to be due to cervical weakness. Investigations were normal. Please select your answer A. Low dose Aspirin B. Serial Cervical length ultrasound scan C. Prednisolone D. HCG E. Low molecular weight Heparin F. Metformin G. Hysteroscopic resection H. Intravenous immunoglobulin I. Cervical cerclage J. Reassurance K. Progesterone pessary L. Low dose Aspirin & LMW Heparin M. Weight reduction 12. A 30 year old woman investigated for 3 recurrent 1st trimester pregnancy losses, is found to have high titres of anticardiolipin antibodies. Please select your answer A. Low dose Aspirin B. Serial Cervical length ultrasound scan C. Prednisolone D. HCG E. Low molecular weight Heparin F. Metformin G. Hysteroscopic resection H. Intravenous immunoglobulin I. Cervical cerclage J. Reassurance K. Progesterone pessary L. Low dose Aspirin & LMW Heparin M. Weight reduction 13. A 34 year old woman being investigated for recurrent 1st trimester Pregnancy losses. She is obese with a BMI of 33 and a family history of diabetes mellitus. She has been diagnosed to have PCOS. No other cause has been found. Please select your answer A. Low dose Aspirin B. Serial Cervical length ultrasound scan C. Prednisolone D. HCG E. Low molecular weight Heparin F. Metformin G. Hysteroscopic resection H. Intravenous immunoglobulin I. Cervical cerclage J. Reassurance K. Progesterone pessary L. Low dose Aspirin & LMW Heparin M. Weight reduction 14. A 32 year old woman had investigations abroad for recurrent first trimester Pregnancy losses. She was very apprehensive and was extensively investigated. All investigations were normal except for endometrial Natural Killer cells testing was abnormal. Please select your answer A. Low dose Aspirin B. Serial Cervical length ultrasound scan C. Prednisolone D. HCG E. Low molecular weight Heparin F. Metformin G. Hysteroscopic resection H. Intravenous immunoglobulin I. Cervical cerclage J. Reassurance K. Progesterone pessary L. Low dose Aspirin & LMW Heparin M. Weight reduction 15. A 26 year old lady has been investigated for recurrent first trimester pregnancy losses. A luteal phase defect has been the working diagnosis. She is now pregnant and it is a natural conception. Please select your answer A. Low dose Aspirin B. Serial Cervical length ultrasound scan C. Prednisolone D. HCG E. Low molecular weight Heparin F. Metformin G. Hysteroscopic resection H. Intravenous immunoglobulin I. Cervical cerclage J. Reassurance K. Progesterone pessary L. Low dose Aspirin & LMW Heparin M. Weight reduction 16. A couple are seen in the gynaecology clinic after their third miscarriage.The karyotyping is normal. Thrombophilia screening is negative. Pelvic ultrasound is normal. Please select your answer A. Low dose Aspirin B. Serial Cervical length ultrasound scan C. Prednisolone D. HCG E. Low molecular weight Heparin F. Metformin G. Hysteroscopic resection H. Intravenous immunoglobulin I. Cervical cerclage J. Reassurance K. Progesterone pessary L. Low dose Aspirin & LMW Heparin M. Weight reduction Time's up StudyMEDIC2020-11-13T09:03:49+00:00