EBCOG Part 1-Menopause

1.Hormone replacement therapy (HRT):

A Increases the risk of colon cancer

B Increases the risk of a brain tumour

C Increases the risk of stroke

D Increases the risk of coronary heart disease

E Increases the risk of venous thromboembolism (VTE)

2.Hormone replacement therapy (HRT) is indicated:

A To prevent Alzheimer disease

B To treat overactive bladder

C To treat psychosis in postmenopausal women

D To treat severe vasomotor symptoms in postmenopausal women

E To treat vulval dystrophic disorders

3.Lichen sclerosus is associated with:

A Type 1 diabetes mellitus

B Vaginal cancer

C Alopecia areata

D Primary biliary cirrhosis

E Labial adhesions

4.With regards to premature ovarian failure:

A It is associated with osteoporosis

B One of the most common chromosomal causes is trisomy 13

C The classic picture is raised steroid hormones with decreased follicle- stimulating hormone (FSH)

D It can occur in women with galactosaemia

E Women diagnosed with this condition require only cyclical oestrogen therapy as progesterone is produced peripherally

5. With regards to VTE:

A Oral oestrogen HRT increases the risk of VTE three-fold in the first year of use

B Raloxifene is associated with a three-fold increase in risk of VTE in the first year of use

C Progestogen only pill used for contraception significantly increases the risk of VTE

D The risk of postoperative deep venous thrombosis (DVT) following major surgery is roughly doubled in women taking a combined oral contraceptive pill(COCP)

E The risk of VTE is 40 in 100,000 in postmenopausal women who do not use HRT

6.HRT:

A Decreases the risk of breast cancer

B Increases the risk of osteoporotic fractures

C Increases the risk of thrombosis

D Increases the risk of stroke

E Reduces the risk of colorectal cancer