Recurrent Pregnancy Loss

1. Which of the following age groups is associated with the smallest risk of miscarriage?

A. 12–19 years.
B. 20–24 years.
C. 25–29 years.
D. 30–34 years.
E. 35–39 years

2. What percentage of these women have antiphospholipid antibodies?

A. 5%
B. 10%
C. 15%
D. 25%
E. 40%

3. A couple who have had three consecutive miscarriages have come to see you for advice after having a thrombophilia screen. The result showed that she was positive to one of the antiphospholipid antibodies. Which of the following is an antiphospholipid antibody?

A. Anti-B2-glycoprotein-1 antibody
B. Anti-B1-glycoprotein-1 antibody
C. Anti-B2-glycoprotein-2 antibody
D. Anti-B2-glycoprotein-3 antibody
E. Anti-B3-glycoprotein-1 antibody

4. The population of cells in the endometrial stroma varies with the time of the menstrual cycle.
What proportion of the leucocyte population of the endometrial stroma during the later secretory phase is made up of uterine natural killer cells?

A. At least 10%
B. At least 20%
C. At least 30%
D. At least 40%
E. At least 50%

5. What is the Risk of miscarriage after 6 consecutive miscarriages for a couple?

A. 30%
B. 40%
C. 50%
D. 60%
E. 70%

6. Women with history of 3 recurrent miscarriages, on investigation found to have anticardiolipin antibodies positive in her initial visit were high, what is the advice that the woman should be given about results:

A. Repeat test after 6 weeks
B. Repeat test after 12 weeks
C. Aspirin in the next pregnancy
D. Aspirin + LMWH in next pregnancy
E. Reassurance

7. The most important predicting factor for early pregnancy loss is

A. Age of the female
B. Age of the male
C. Smoking
D. Obesity
E. Chronic endometritis

8. Regarding parental genetic testing, the following statement is true:

A. Parental karyotype is routinely recommended for all the couples with RPL
B. Parental karyotyping should be done for couple with previous birth of a child with congenital anomalies, offspring with unbalanced chromosome abnormalities in the family, or detection of a translocation in the pregnancy tissued
C. For couple with a parental chromosome abnormality, about 50% are caused by chromosome abnormalities and the other loses are due to aneuploidies, unexplained or other underlying factors
D. No increased chance of a subsequent pregnancy loss in case of a carrier state
E. Good chance of live born child with an unbalanced chromosome abnormality for the whole population

9. Which of the following interventions have been shown to be effective in reducing the risk of further miscarriage in unexplained recurrent miscarriage:

A. Reassurance and tender loving care
B. Progesterone therapy
C. Aspirin 75 mg from the time of visualization of fetal cardiac activity
D. Aspirin before 16 weeks
E. Aspirin and low molecular weight heparin

Recurrent Pregnancy Loss

Recurrent Pregnancy Loss

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